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Natural Brain Boosters

Sharpen memory and focus with omega 3 and more

By Victoria Dolby Toews, MPH

Everyone wants a sharp mind—from college students who want better focus to older adults concerned about age-related memory problems.

It’s not uncommon to experience a little brain fog now and again. The culprit is often elevated levels of cortisol. This stress hormone can, over time, damage the brain’s memory center, called the hippocampus, said Holly Lucille, ND, nutritionist and author of Creating and Maintaining Balance: A Woman's Guide to Safe Natural Hormone Health.

Nutrients to Support Your Brain

  • Omega 3s for Improved Memory & More

    It turns out that “fathead” should be considered a compliment, not an insult. The human brain is made up of a significant amount of fat, which it needs to run properly. Supplementing with the right fats helps make sure everything keeps humming along.

    Omega-3 essential fatty acids contribute a lot to the brain, such as providing nutrients critical for the structure and function of brain cells. Research indicates that regular consumption of the omega-3 fatty acids EPA and DHA results in improved cognition and better memory.

    If you don’t eat fish several times a week, consider taking 500 to 1,000 mg of an omega-3 supplement each day. Some studies show more consistent effects with 1,000 to 2,500 mg/day, but evidence quality varies. Do not exceed more than 2 g/day EPA+DHA from supplements without medical guidance.

  • Vitamin C for Endurance

    Since stress is such a brain drainer, supporting antioxidant protection and neurotransmitter-related processes can help clear up your thinking. The key nutrient is vitamin C.

    “During stress, the adrenal glands stockpile this antioxidant to protect against free-radical damage. However, ongoing stress depletes this vital nutrient from the adrenal glands,” Dr. Lucille says.

    One randomized trial found vitamin C supplementation improved focus in healthy young adults with inadequate vitamin C stats. 

    She recommends at least 250 to 500 milligrams (mg) per day of vitamin C for anyone concerned with managing stress and preserving clear thinking.

  • L-tyrosine to Respond to Stress

    Another of Dr. Lucille’s favorite ways to perk up the mind is supplementing with L-tyrosine. This amino acid, found in cheese and yogurt, helps both mind and body respond to stressful situations.

    Common supplemental amounts range from 500 to 1,000 mg of L-tyrosine daily, often taken before mentally demanding or stressful tasks. 

  • Cocoa Flavanols for Cognition

    Supplementing with cocoa flavanols may benefit people with poorer diet quality. Choose minimally processed cocoa/dark chocolate if you are choosing it in food form.

"A systematic review and dose response meta analysis of Omega 3 supplementation on cognitive function" by H. Shahinfar et al., Scientific Reports, 8/10/25

"Cocoa flavanol consumption improves cognitive function . . . in elderly subjects: the Cocoa, Cognition, and Aging (CoCoaA) Study--a randomized controlled trial" by D. Mastroiacovo et al., American Journal of Clinical Nutrition

“Docosahexaenoic acid–rich fish oil modulates the cerebral hemodynamic response to cognitive tasks in healthy young adults” by P.A. Jackson et al., Biological Psychology

Personal communication: Holly Lucille, ND, RN

Contributor

Victoria Dolby Toews, MPH

Victoria Dolby Toews, MPH, is an evidence-based, integrative medicine journalist with more than 20 years of research and writing expertise, She received her Master of Public Health from OHSU-PSU School of Public Health.

She is the author or co-author of numerous books, including Life After Baby (2012), The Green Tea Book, 2nd edition (Penguin, 2008). User’s Guide to Healthy Digestion (Basic Health Publications, 2004), The Soy Sensation (McGraw-Hill, 2002), User’s Guide to Glucosamine and Chondroitin (Basic Health Publications, 2002), The Common Cold Cure (Avery, 1999), and The Green Tea Book (Avery, 1998).

Her work was recognized for excellence as a 2001 finalist for the Maggie Awards (Western Publications Association award honoring editorial excellence in magazines west of the Mississippi River).

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