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Why Your Skin Needs Ceramides After 40

Supportive topical products and foods

By Nan Fornal

If it seems like your skin has been getting progressively drier and more reactive as you get older, you’re not imagining it. 

As we age, the skin’s natural protective barrier begins to weaken—and one of the biggest reasons is a decline in the body’s production of ceramides.

These natural fats, members of the sphingolipid family, are found in the outermost layer of skin, where they help keep moisture in. Think of skin cells as bricks—ceramides are the mortar that holds everything together. When ceramide levels start to decline, skin can become dry, sensitive, flaky, and easily irritated.

This can leave skin feeling thinner, rougher, and less able to bounce back.

What Are Ceramides?

Ceramides make up 50 percent of the outer skin layer barrier. But they do more than keep the skin surface moist. They actively repair and maintain the skin barrier itself, something which becomes increasing important as skin ages or becomes stressed by harsh weather, aggressive skin care routines, excessive exfoliation, and too much sun exposure.

Ceramide deficiencies are linked with atopic dermatitis, eczema, and psoriasis. Researchers are in the early stages of testing the usefulness of ceramides in fighting serious conditions such as skin cancer.

Support Your Natural Ceramide Production

Feed your skin from within by eating nutrient-rich, anti-inflammatory foods. Choose omega-3–rich foods such as salmon, sardines, walnuts, and flax as well as sphingolipid-rich foods such as dairy, brown rice, sweet potatoes, eggs, soybeans, and meat—especially poultry. 

Improving your gut health will help improve your skin. Focus on getting plenty of fiber in your diet, eating more fermented foods to support gut microbiome diversity, and avoiding ultra-processed foods. Stay well hydrated, manage the stress in your life, keep physically active every day, and get enough sleep.

How to Use Ceramides

For best results, use products that combine ceramides with other ingredients that are good for the skin. Three categories to look for are emollients, humectants, and occlusives. Emollients help relieve dry and itchy skin; humectants attract moisture; and occlusives lock in moisture—and don’t dissolve in water.

In addition to ceramides, check skincare product labels for glycerin, colloidal oatmeal, hyaluronic acid, and shea butter. For maximum absorption, use these products on damp skin.

Topical moisturizers containing ceramides have been shown to help prevent skin dryness and irritation for people undergoing acne treatment. People with dry, eczema-prone skin who used ceramide-containing creams found improved skin barrier function and hydration after use. Ceramides are also used in medical settings for eczema, very dry skin, and for a compromised skin barrier.

 

 

 

“Ceramides and skin health: New insights” by T.L. Yong et al., Experimental Dermatology, 2/25

“A daily regimen of a ceramide-dominant moisturizing cream and cleanser restores the skin permeability barrier in adults with moderate eczema: A randomized trial” by F. Spada et al., Dermatologic Therapy, 5/24/21

“Function of ceramides in the skin and its relationship with skin disease” by W. Huang et al., Journal of Steroid Biochemistry and Molecular Biology, 8/11/25

“Moisturizers and ceramide-containing moisturizers may offer concomitant therapy with benefits” by C.W. Lynde et al., Journal of Clinical and Aesthetic Dermatology 

“What are ceramides?” https://health.clevelandclinic.org, 4/15/25

 

Contributor

Nan Fornal

Nan Fornal has experience with fiction, nonfiction, and technical publications, working closely with book and magazine publishers from first edit to final proofing. She has worked with Exeter Press, Boston magazine, and self-publishers alike.

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Nutraceuticals and Herbs for Cervical Dysplasia

Supportive integrative strategies

By Dr. Silmacoral López Jiménez

Although it’s one of the most preventable forms of cancer, cervical cancer remains one of the most common among women worldwide. Most cervical cancers develop from cervical dysplasia, a condition in which abnormal cells form on the cervix, usually as a result of infection with high-risk strains of the human papillomavirus (HPV). When HPV infections do not clear naturally, they can lead to cervical intraepithelial neoplasia (CIN) and, over time, cervical cancer.

Many HPV infections resolve on their own, but some factors increase the risk of persistent infection and progression. These include smoking, immune suppression, multiple sexual partners, co-infections, early sexual activity, and nutritional deficiencies. Because cervical dysplasia represents a window of opportunity before cancer develops, supportive therapies may play an important role in prevention and recovery.

Conventional Treatment & the Role of Integrative Care

Management of cervical dysplasia depends on the severity of abnormal cells. Low-grade lesions are often monitored because many regress spontaneously. Persistent or high-grade lesions may be removed. While effective, removal doesn’t address viral persistence, immune function, or tissue repair. This has led to growing interest in integrative and naturopathic approaches that support the body’s ability to clear HPV, repair cervical tissue, and restore a healthy vaginal environment.

Key Nutrients for Cervical Health

  • Folate and vitamin B12 support viral regulation and healthy cell growth. Adequate levels may reduce HPV persistence and disease progression, while deficiencies are linked to increased persistence and abnormal cervical cell changes.
  • Hyaluronic acid is known for skin hydration. In cervical health, it helps restore the protective mucosal barrier and promote healing of the cervical lining. Vaginal use may aid tissue repair and help support spontaneous viral clearance in low-grade cervical lesions, particularly when combined with other reparative compounds.
  • Green tea contains antioxidant catechins, especially EGCG, which has anti-inflammatory, antiviral, and anti-proliferative properties. It may inhibit HPV-positive cervical cell growth, promote apoptosis (death of abnormal cells), and support immune function. Studies evaluating oral and vaginal green tea preparations show improvement in low-grade cervical lesions.
  • Diindolylmethane (DIM), a compound derived from cruciferous vegetables, supports healthy estrogen metabolism and may help shift estrogen pathways toward those associated with lower cancer risk. This mechanism may help reduce proliferation of HPV-affected cervical cells.
  • Coriolus versicolor, commonly known as turkey tail mushroom, has been studied for its immune-modulating and antiviral properties. Topical vaginal gels and oral supplements containing Coriolus versicolor have shown benefits in improving cervical tissue repair, supporting HPV clearance, and promoting a healthy vaginal microbiome. These products are often combined with hyaluronic acid and herbal ingredients, including aloe and neem.

The Vaginal Microbiome

The vaginal microbiome is key to cervical health. A Lactobacillus-dominant environment (e.g., L. crispatus, L. gasseri, L. reuteri) helps maintain an acidic environment and protect against pathogens. Reduced levels are linked to HPV persistence and dysplasia progression, making probiotics a potentially important support strategy.

Immune Support & HPV Clearance

AHCC, a standardized extract derived from shiitake mushroom mycelia, has been studied for immune support and viral infections. While additional research is needed, clinical studies show promising results in AHCC’s ability to support immune function and aid in the clearance of persistent HPV infections.

Note

Any woman interested in integrative approaches should work with a licensed healthcare provider who can develop an individualized plan that incorporates naturopathic medicine as a standalone approach and/or alongside conventional medical care.

“AHCC supplementation to support immune function to clear persistent human papillomavirus infections” by J.A. Smith et al., Frontiers in Oncology, 2022 

“The association of four natural molecules—EGCG, folic acid, vitamin B12, and HA—to counteract HPV cervical lesions . . .” by G. Grandi et al., Journal of Personalized Medicine, 3/22/23 

“Double-blind randomized placebo-controlled multicenter clinical trial (phase IIa) on diindolylmethane’s efficacy and safety in the treatment of CIN . . .” by L. Ashrafian et al., EPMA Journal 

“Efficacy of Coriolus versicolor–based vaginal gel in women with human papillomavirus–dependent cervical lesions . . .” by L. Serrano et al., Journal of Lower Genital Tract Disease, 2021 

“Interactions between serum folate and human papillomavirus with cervical intraepithelial neoplasia risk . . .” by J. Yang, et al., American Journal of Clinical Nutrition, 2018 

“Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions” by W-S Ahe et al., European Journal of Cancer Prevention 

“Therapeutic efficacy of Coriolus versicolor–based vaginal gel in women with cervical uterine high-risk HPV infection . . .” by A.A. Criscuolo et al., Advances in Therapy, 2/21 

The Women’s Encyclopedia of Natural Medicine: Alternative Therapies and Integrative Medicine for Total Health and Wellness by Tori Hudson, ND (McGraw-Hill, 2007)

Contributor

Dr. Silmacoral López Jiménez

Dr. Silmacoral López Jiménez is a naturopathic physician specializing in women’s health and natural medicine. She is on the faculty at the UAGM Gurabo School of Naturopathic Medicine and works as a public speaker and as a clinician at Nature Med Center, her clinic in San Sebastián, Puerto Rico.

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Value Your Veins

Strategies to prevent and treat CVI

By Claire Sykes

Sixty thousand miles—that’s the length of your vascular system. What a journey for your blood! Make it a healthy one.

Your heart pumps blood to your lungs for oxygen, then into your arteries carrying it down to your feet. Calf-muscle contractions push the blood toward your heart, while valves in your calf veins prevent backflow. If valves are weakened or damaged, blood pools in your calf veins, leading to chronic venous insufficiency (CVI). 

Although CVI is irreversible, you can manage and treat it, and maybe even prevent it altogether.

Causes of Chronic Venous Insufficiency

CVI can take years to progress without you knowing, as pressure gradually builds in your leg veins. This happens from prolonged standing or sitting, limited exercise, obesity, pregnancy, or a leg injury or surgery. Smoking can damage veins, which also can weaken with age. Or CVI could run in the family.

“The condition can affect one or both legs. Swelling of the calves and feet is the most common symptom. Second is varicose veins, bulging and twisted veins. With severe insufficiency, skin changes can develop and a wound from an injury in that area may not heal well because of poor blood flow,” says Dr. Lai Chim Chan, ND, associate professor at the National University of Natural Medicine, in Portland, Oregon.

Take Action Against CVI

See your healthcare provider as soon as you notice symptoms. “Mimics include diabetes, heart or kidney problems, hypothyroidism, or lymphedema,” says Chan. “If your legs feel heavy, a venous duplex ultrasound shows how leaky your valves are. Laser treatment for them and/or medicine injected into your veins could help.”

Most likely you can manage—and prevent—CVI with regular exercise that strengthens calf muscles, such as walking uphill or briskly. Compression socks can improve blood flow and reduce swelling, so wear them if you’ll be sitting or standing for a while (your doctor may prescribe them for all-day wear). And take breaks to move your legs and elevate them above your heart.

Drink plenty of water and eat anti-inflammatory foods, including those with flavonoids found in many colorful fruits and vegetables, such as blueberries, red cabbage, and kale.

Supplements for CVI

Chan suggests these herbal extracts for CVI: horse chestnut (Aesculus hippocastanum L.), butcher’s broom (Ruscus aculeatus), French maritime pine bark (Pycnogenol) and grapeseed (Vitis vinifara). Then there’s gotu kola (Centella asiatica). “Consult with your doctor for the right herbs and doses for you,” she urges.

It’s never in vain to care for your veins, CVI or not. A healthy vascular system assures a happy heart.

Horse-chestnut seed extract for chronic venous insufficiency. A criteria-based systematic review by M.H. Pittler and E. Ernst, Archives of Dermatology

Personal Communication: Lai Chim Chan, ND

Therapeutic applications of natural products in the management of venous diseases: a comprehensive review by R.E. Mustafa et al., Inflammopharmacology, 4/25

Varicose veins and occupational health: Symptoms, treatment and prevention by D. Camargo de Lima, Revista Brasileira de Medicina do Trabalho, 12/1/19

Contributor

Claire Sykes

Claire Sykes is a freelance writer based in Portland, Oregon.

She loves that she's always learning about something new, and gets to talk with a wide variety of people, often at such an extent or depth.

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Perfecting the Paleo Diet

By Lili Hanft

Are you thinking of trying the popular paleo diet? Inspired by the diet of our Paleolithic ancestors, the paleo diet emphasizes whole, unprocessed, high-quality meats and vegetables while excluding grains, legumes, sugar, most dairy, and refined vegetable oils.

Many people believe it helps them with health challenges ranging from digestive issues to hormonal imbalances.

With the Paleo Diet, Simplicity is Key

When eating paleo, it’s best to keep it simple if you want to increase your chance of success. While a Google search for “paleo recipes” will turn up countless “paleo-ified” versions of everything from bagels to brownies, these recipes can contain expensive, hard-to-find ingredients that aren’t as nutritious as simpler whole foods.

Simple foods that you likely already know how to cook can make a delicious paleo menu: fried eggs with a side of fresh berries for breakfast; a big salad topped with salmon and avocado for lunch; a bunless burger with a baked sweet potato and roasted broccoli for dinner; almonds and an apple for a snack.

As an added bonus, keeping your paleo diet simple will help you stick to a budget. Focus on the basics: meat, fish, eggs, loads of colorful veggies, some fruits, and fats such as coconut, avocado, and butter. If you have extra room in your budget, you can opt for grass-fed meats and packaged paleo snack bars and protein powders.

Be Prepared with Paleo Meal Prep

Another way to spare your wallet (and your sanity) when going paleo is to focus on meal prep. Consider cooking grass-fed ground beef with lots of veggies (think carrots, broccoli, kale, onion, mushrooms, and the like) on the weekend so you can have meals ready to go during the week. Other paleo staples that can be prepared in advance include hard-boiled eggs, baked sweet potatoes, trail mix, and hearty soups. Having your fridge and freezer stocked with premade, healthy options makes sticking to a paleo diet easier during busy weeks.

Finally, as you make the transition to this ancestral way of eating, listen to your body. Rather than seeing a non-paleo indulgence as a slip-up, see it as a chance to observe how your body feels when you eat different foods. At the end of the day, the best determinant of your ideal diet is how it makes you feel.

Further Reading

Contributor

Lili Hanft

Lili Hanft Hanft is a Functional Nutritional Therapy Practitioner. She works with clients to help them nourish their bodies, feel confident in the kitchen, and tailor their diets to their unique needs and health goals. Lili teaches virtual cooking classes focused on simple, nutrient-dense recipes and meal prep. Learn more on her website and follow her on instagram.

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Mold Sickness

The Secret Behind Your Symptoms?

By Marsha McCulloch, MS, RD

An estimated 24 percent of the population have genetics that put them at increased risk for chronic health problems from mold exposure. They often end up with vague diagnoses like chronic fatigue syndrome, multiple chemical sensitivity, or irritable bowel syndrome.

Symptoms of Mold Illness

“Symptoms commonly include fatigue, brain fog, headaches, anxiety, gut disruptions (like gas, bloating, or diarrhea), skin rashes, frequent urination, and insomnia,” says Jill Crista, ND, author of Break the Mold ($24.95, Wellness Ink Publishing, 2018). “Frequent vision changes and ear ringing are also common.”

Try her online screening test.

How Mold Hurts You

Mold off-gases harmful chemicals, including volatile organic compounds (VOCs) and mycotoxins, that can erode your health. This can happen in a home with:

  • a damp basement
  • undetected leaks
  • humidity level is too high

“Mycotoxins can be taken in through your nose, mouth, or skin,” says Matt Pratt-Hyatt, PhD, a microbiologist and director of research at the Mold Pros in Kansas City, MO. “Then they can enter your cells, causing damage and interfering with energy production.” Mold VOCs can also be inhaled and cause inflammation.

The cellular damage caused by mold can disrupt multiple systems in your body. “The nervous system, immune system, and gastrointestinal system tend to get the brunt of the attack,” Dr. Pratt-Hyatt says. The system hit the hardest tends to vary with a person’s genetics.

How to Tell If Your Home Has Mold

Mold Doesn't Always Smell

Even if you don’t notice a musty odor, mold could be hiding.

“Stachybotrys, which is a well-known black mold, frequently produces a smell,” Dr. Pratt-Hyatt says. “But there are many other kinds of mold, like Aspergillus and Penicillium, that don’t have an odor but produce very harmful mycotoxins.”

Consider an Environmental Mold Test

To screen your home for mold, consider the Environmental Mold & Mycotoxin Assessment test (EMMA) offered by RealTime Laboratories. The EMMA test not only tests for mold spores but also mycotoxins. Just realize that if you plan to file a lawsuit, you’ll need a third-party inspection by a certified expert, says Dr. Crista.

Recovering from Mold Sickness

Dealing with Mold Problems

If a mold problem is found, multiple corrective steps are needed. Dr. Pratt-Hyatt advises professional remediation, including removal of moldy building material, enzymatic destruction of mycotoxins, and ultra-low penetration air (ULPA) filtered vacuuming of all interior surfaces of your home.

See a Specialist

To be evaluated, find a healthcare practitioner trained in chronic mold illness, not an allergist.

“A mold allergy test only looks at reactions to spores,” Dr. Crista says. “You can have a normal mold allergy test but still have mold illness.”

Here are three websites that can help you locate mold-savvy practitioners:

Consider Supplements

Dr. Crista recommends these supplements for people with mold illness.

Supplements Against Mold
Supplement Purpose
DHA, EPA, and GLA fatty acids Promote production of bile, which carries out mycotoxins.
Psyllium husk fiber Binds toxin-laden bile, so you excrete it rather than recycle it.
Quercetin An antihistamine that calms inflammation.
Glutathione (liposomal) Promotes detoxification, and is a potent antioxidant.
Oil of Oregano Has antifungal actions to support microbial balance.

 

“HLA-DR: Your genes,” www.survivingmold.com/diagnosis/lab-tests

“Is mold toxicity really a problem for our patients? Part 2—Nonrespiratory conditions” by J. Pizzorno, Integrative Medicine, 6/16

“Moist and mold exposure is associated with high prevalence of neurological symptoms and MCS in a Finnish hospital workers cohort” by S. Hyvonen et al., Safety and Health Work, 6/20

Personal communication: Jill Crista; Matt Pratt-Hyatt

“A review of the mechanism of injury and treatment approaches for illness resulting from exposure to water-damaged buildings, mold, and mycotoxins” by J. Hope, The Scientific World Journal, 2013

“Severe sequelae to mold-related illness as demonstrated in two Finnish cohorts” by T. Tuuminen et al., Frontiers in Immunology, 4/17

“Sick building syndrome (SBS) and exposure to water-damaged buildings . . .” by R.C. Shoemaker et al., Neurotoxicology and Teratology, 2006

Contributor

Marsha McCulloch, MS, RD

Marsha McCulloch, MS, RD, is a holistic dietitian and freelance writer for several natural health magazines and blogs. Follow her on Twitter.

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Lettuce Wrap Shrimp Tacos

with Cilantro-Lime Crema

By The Taste for Life Test Kitchen
Prep Time
30 minutes
Number of Servings
12 tacos (serves 4)
Ingredients
  • Cilantro Crema

    • 12 cup mayonnaise 
    • 14 cup plain Greek yogurt
    • 12 tsp ground cumin
    • Juice of 1 lime
    • 13 cup chopped fresh cilantro
    • Salt
  • Tacos

    • 1 lb large shrimp, peeled and deveined
    • 1 tsp chili powder
    • 12 tsp onion powder
    • 12 tsp salt
    • 2 Tbsp avocado oil
    • 12 large Romaine lettuce leaves
    • 1 cup thinly sliced red cabbage
    • 1 cup thinly sliced white cabbage
    • 1 cup your favorite salsa or Pico de Gallo 
    • Lime wedges for serving
Directions
  1. In a medium bowl, combine mayonnaise, yogurt, cumin, lime juice, cilantro, and salt to taste. Set crema aside while you prepare tacos.
  2. In a large bowl, toss shrimp with chili powder, onion powder, and salt.
  3. Heat oil in a large pan set over medium heat. Add shrimp and cook 2 to 3 minutes per side, until shrimp are pink in color and cooked through.
  4. Place lettuce leafs on a clean work surface. Divide equal amounts of cooked shrimp, red cabbage, and white cabbage over each lettuce leaf. 
  5. Drizzle cilantro crema and salsa over each lettuce leaf taco. Serve with lime wedges to squeeze over.
Nutrition Info

423 Calories, 26 g Protein, 196 mg Cholesterol, 13 g Carbohydrates, 6 g Total sugars (0 g Added sugars), 4 g Fiber, 31 g Total fat (5 g sat), 803 mg Sodium, ★★★★ Vitamin K, Phosphorus, ★★★ Vitamin C, Vitamin A, Vitamin B6, Calcium, Folate, Iron, Magnesium, Potassium, Zinc

Contributor

The Taste for Life Test Kitchen

The Taste for Life staffers have a wide variety of backgrounds and dietary needs. We're always experimenting in the kitchen, and love to share what we cook—and what we learn in the process.

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Making Sense of the Mushroom Boom

A guide to confident supplement shopping

By Bill Chioffi
Man in a greenhouse holding up Maitake mushroom.

Photos courtesy of Nammex Mushrooms, Inc.

If you feel that mushrooms are suddenly everywhere from your morning coffee to your nightly skin care routine, you aren’t imagining it. The shroom boom is in full swing, and for good reason. As we prioritize overall well-being with a focus on cognitive health and immune resilience in 2026, functional fungi have moved from the fringes of herbalism into the mainstream spotlight.

However, as mushrooms become a multibillion-dollar industry, the market has become crowded and, frankly, confusing. When you are spending $40 to $60 on a bottle of capsules, you deserve to know what you’re paying for. This guide is designed to help you decode labels with confidence.

Why Mushrooms, and Why Now?

The surge in popularity is driven by a post-pandemic focus on immunity and a fascination with nootropics (brain boosters). But the real driver is science. 

In 2026, we are seeing more standards, analytical science, and clinical studies than ever before. We are moving beyond traditional use into data-driven results, particularly regarding how fungal compounds interact with our nervous and immune systems.

Understanding the Label

The most critical distinction is which part of the fungal organism is being consumed. A mushroom describes the above-ground, fleshy fruiting body of a fungus. It develops from mycelium when environmental conditions are suitable. Mushroom (also known as the fruit body, fruiting body, or sporocarp) is the fungal part or mature stage that produces spores and the form commonly eaten as nutritious food.

Mycelium is the vegetative growth form of the fungus, consisting of a network of hyphae, the fine threadlike filaments that grow within and around their food source, e.g., woody debris, soils, grasses, or other organic matter. Many commercial mycelium products, specifically those produced in the US, are grown on and contain grain.

Notably, fungi lack starch; if a product tests high for starch, that identifies the residual grain used as a food source for the mycelium rather than fungal material.

Delivery Methods

Processing determines how much of the “good stuff” your body can use.

• Dual extract and extract powders

These are considered the most effective preparations for species like reishi, lion’s mane, chaga, cordyceps, or turkey tail. Mushrooms contain both water-soluble compounds (beta-glucans) and fat-soluble ones (triterpenes). These compounds are packed within a substance called chitin (the same stuff that makes lobster shells hard). A dual extract uses hot water and alcohol to ensure you get both components. 

• Tinctures and liquid extracts

Tinctures and liquid extracts are available; however, many of the well-studied, health-supporting properties of mushrooms come from their unique fiber content. Extracts in glycerine or alcohol will have very little of this fiber, and therefore much lower beta-glucan content compared to whole mushroom or extracted powders.

• Powders 

Straight powders are dried, ground fungi. They can be harder to digest than botanical powders because mushroom cell walls contain chitin. Powders that have been cooked or decocted before drying are partially broken down, which can improve bioavailability. Mycelium-fermented grain or products marketed as full-spectrum mushroom powders of US origin contain substantial amounts of the grain used to grow the mycelium.

• Functional foods

Mushroom-infused coffees are convenient, but check the dosage. Ensure you are getting a therapeutic 500 to 1,000 milligrams rather than a sprinkling. Seek out more information on products claiming “full spectrum” or “all parts” of the fungi as to what they include in the product—those terms have no defined meaning, and most of those products will contain rice, oats, or some other grain as part of the biomass.

The “Big Five” Species to Watch

  • Lion’s mane (Hericium erinaceus): The “smart mushroom.” Recent human trials support its ability to stimulate nerve growth factor (NGF) for focus and memory.
  • Turkey tail (Trametes versicolor): A powerhouse for the immune system and one of the most researched mushrooms globally for its protein-bound polysaccharides.
  • Cordyceps (Cordyceps militaris): Known for cellular energy and popular among athletes for improving oxygen utilization.
  • Reishi (Ganoderma lucidum): The “Queen of Mushrooms,” used for stress support and helping modulate the body’s cortisol response.
  • Maitake (Grifola frondosa): Excellent for metabolic health and blood sugar support.

Smart Shopping Checklist: Decoding the Chemistry

Before you head to the checkout, look for these

three markers of quality:

Check to see if the product label lists specific secondary metabolites or betaglucans. General polysaccharide counts are often inflated by grain starches. Look for a breakdown of compounds like triterpenes for reishi or hericenones for lion’s mane and for beta-glucan values. These metabolites drive the mushroom’s unique health benefits.

Is the extraction method specified? If a label doesn’t mention dual extraction or hot water extraction, you may be buying a product your body cannot fully digest.

Is there a clear fungal part breakdown? An FDA-compliant label states whether the product contains 100 percent mushroom (fruiting body), mycelium, mycelium-fermented grain, or a blend. Knowing the part used is the only way to verify potency against clinical research.

Mushrooms are an investment in your long-term wellness. By focusing on extraction methods and fungal parts, you can ensure your supplements are as effective as they are trending.

 

“Cordycepin for health and wellbeing: A potent bioactive metabolite of an entomopathogenic Cordyceps medicinal fungus and its nutraceutical and therapeutic potential” by S.A. Ashraf et al., Molecules, 6/12/20 

“Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers . . .” by K. Pallav et al., Gut Microbes

 “Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment . . .” by K. Mori et al., Phytotherapy Research 

“Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake” by M. Nagano et al., Biomedical Research 

“Unveiling the full spectrum of maitake mushrooms: A comprehensive review of their medicinal, therapeutic, nutraceutical, and cosmetic potential” by E. Camilleri et al., Heliyon, 4/26/24

 

Contributor

Bill Chioffi

COO Nammex Mushrooms, Inc.

Bill Chioffi is an expert in herbal supply chains and botanical research. He is the chief operating officer at Nammex Mushrooms, Inc., a leading supplier of organic mushroom extracts, and an advocate for mushroom education and rigorous quality standards and practices in the industry.

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Shatavari

What can this traditional herbal remedy do for you?

By Maria Noël Groves, RH (AHG)

Are hormone wobbles, menopause symptoms, stress, or insomnia bogging you down? You may find shatavari, the ancient “Queen of Herbs” from India and South Asia, a fantastic ally. 

Revered for millennia in its homelands, shatavari has recently become more popular in the West, with several new studies supporting its traditional benefits. “Shat” means 100 while “vri” means root or husband, often translated to “100 roots” (for its multirooted appearance) or “she who possesses 100 husbands” (for its long-held tradition for reproductive, hormone, and sexual vitality).

What Is Shatavari?

This is the medicinal root of Asparagus racemosa, different from but related to the asparagus we eat as a vegetable. It has nourishing, moistening, adaptogenic, yin tonic, nervine, and anti-inflammatory properties with a particular affinity for the reproductive, urinary, digestive, and nervous-adrenal systems, particularly as a supportive herb for estrogen-associated health markers.

Traditional Benefits of Shatavari

Shatavari is revered in the Ayurvedic healing tradition as a tonic for reproductive hormone vitality through the various phases of life: sexual vitality; fertility and milk production; mood, strength, and resilience; and better vitality throughout the aging and menopause processes. 

Active Compounds

Shatavari contains various constituents that likely contribute to its many health benefits. 

Shatavarins fall within the class of steroidal saponins, constituents common in adaptogenic and reproductive tonic herbs. Shatavarins are linked with this herb’s benefits for stress reduction and resilience; balanced mood, sleep, and energy; brain health; and both reproductive and adrenal hormone balance. 

Isoflavones in shatavari provide phytoestrogenic actions that support estrogen and estrogen-associated health benefits, reproductive hormone balance, and vitality from menarche through menopause.

Mucilage gives shatavari a slippery, soothing, moistening “juicy” energy, particularly for mucosal membranes including cervical fluid and in the digestive and urinary tracts, particularly helpful alongside the phytoestrogenic benefits.

Evidence-Based Benefits

While science on shatavari has been historically limited, a surge of recent studies has confirmed its traditional benefits and increased awareness and popularity here in the United States.

Menopause, Hot Flashes, Sleep, Stress, Fatigue: Several studies of peri- and post-menopausal participants have shown shatavari extract to dramatically improve sleep quality (by 60 to 90 percent), reduce hot flashes (by 85 to 90 percent), reduce overall menopause symptoms (about 70 percent), and decrease fatigue, anxiety, and stress.

Estrogen: Subtle improvements in estradiol estrogen and follicle stimulating hormone levels in perimenopausal participants.

Sexual Vitality: Studies have also confirmed reduction of vaginal dryness and improved sexual function and pleasure.

Strength: Preliminary studies suggest slight improvements in muscle strength and bone health in older women, though longer studies are needed.

Nursing and Milk Production: Shatavari’s long-held reputation as a galactagogue has also been confirmed. In one study this resulted in approximately 15 milliliters more milk and eight fewer hours to breast fullness than in the placebo group.

At this time, much of the research on shatavari is influenced by, funded by, and/or conducted on specific brands of specialty shatavari extracts. While these study results do mirror traditional reputation and my own clinical experience, more independent research conducted on the crude roots is needed.

Dosages and How to Take

Shatavari root is taken in a few different formats. Standardized extracts may be more potent and can be taken in lower doses; though crude root medicines are traditional. Opt to take it at a convenient time of day, such as with breakfast.

Standardized root extracts in pill form: 300–600 milligrams (mg)/day

Crude pills or powder: 500–1,000 mg/day 
or up to ¼ to ½ teaspoon once or twice a day (½ teaspoon = about 1,000 mg)

Tea: gently simmer ¼ to ½ teaspoon powder or ½ to 1 teaspoon cut/sifted root in 8–16 ounces of water, hot milk, ghee, or broth for 10–20 minutes or let infuse (steep) overnight solo or in blends

While some people notice a difference with shatavari quickly, most see the impacts slowly and subtly build up over two months and with consistent and continued consumption to maintain the benefits, feeling it with a more even-keeled mood, less fatigue without overstimulation, better sleep, improved sexual function and libido, increased stress resilience, and fewer hot flashes and night sweats.

It is often taken solo or combined with other hormone-balancing or adaptogenic herbs. Several studies support its benefits alongside ashwagandha for added stress, mood, energy, strength, and libido support. 

In my clinic, I often pair it with pumpkin seed oil extract pills for estrogen and bladder benefits, especially for menopause, and for support for hot flashes, sleep, stress, and urinary frequency or incontinence.

Safety/Side Effects

Shatavari is generally well tolerated with few or no side effects. In large quantities, it may aggravate gas and bloating due to its fibrous mucilage properties; however, this is extremely rare in the dose ranges recommended. 

One study in people with polycystic ovarian syndrome (PCOS) noted increased endometrial thickness after 12 weeks of use versus baseline and placebo; however, it’s unclear at this time if this was problematic or a sign of enhanced endometrial quality and function.

Asparagus racemosus root extract (SheVari4®) alleviates menopausal symptoms in pre-, peri-, and post-menopausal healthy women” by A. Swaroop et al., 4/13/26; “Efficacy and safety of shatavari root extract for the management of menopausal symptoms: A double-blind, multicenter, randomized controlled trial” by V.S. Gudise et al., 4/8/24, Cureus

“Effects of shatavari (Asparagus racemosus) root extract on sexual wellness in women: Findings from a prospective, randomized, double-blind, three-arm, parallel-group, placebo-controlled study” by J. Ademola et al., 2/26; “Efficacy and safety or shatavari (Asparagus racemosus) for perimenopause: Randomized, double-blind, placebo-controlled study” by S. Mahajan et al., 11/3/25, International Journal of Women’s Health

“Shatavari” by J. Brinkman and M. Williams, HerbalGram, www.herbalgram.org, issue 133 (2022)

Contributor

Maria Noël Groves, RH (AHG)

Maria Noël Groves, RH (AHG), is the best-selling, award-winning author of Herbal Gut Health, Body into Balance: An Herbal Guide to Holistic Self Care, Grow Your Own Herbal Remedies, and Herbal Remedies for Sleep. 

Maria’s a registered professional herbalist with the American Herbalists Guild and a graduate of the Southwest School of Botanical Medicine and Rosemary Gladstar’s Sage Mountain. Learn more about Maria and herbs at Wintergreen Botanicals. Find her remedy-making tips at wintergreenbotanicals.com/kitchenapothecary101

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Meet the Immune-Support Superstar Called Beta-Glucan

Found in mushrooms, yeast, and oats, beta-glucans are gaining attention

By The Taste for Life Staff

Beta-glucans are naturally occurring compounds found in the cell walls of certain yeasts, mushrooms, oats, and barley. Best known for their immune-supporting properties, beta-glucans have been studied for their ability to help activate and support key immune cells. 

Different types of beta-glucans exist, but those sourced from baker's yeast and functional mushrooms are popular in immune health supplements. 

How Beta-Glucans Work

Beta-glucans interact with immune cells such as macrophages, neutrophils, and natural killer (NK) cells. Researchers believe they help "train" or prime the immune system to respond more efficiently when needed. Rather than overstimulating immunity, beta-glucans are often described as immune modulators that help support balanced immune function. 

Potential Benefits of Beta-Glucans

In addition to helping support a healthy immune response, research suggests beta-glucans can also help with upper respiratory health and a healthy inflammatory response. 

Some beta-glucans also function as prebiotics, helping nourish beneficial gut bacteria. This is important because much of the immune system is closely connected to the gut. 

Sources of Beta-Glucans

Beta-glucans occur naturally in oats and barley as well as reishi, shiitake, maitake, and turkey tail mushrooms. When shopping for supplements, you may see beta-glucans sourced from yeast as well. Many products combine beta-glucans with other key immune-support ingredients, including zinc, vitamin D, and probiotics. 

Doses

Human studies on beta-glucans for immunity typically use doses ranging from 250 to 1,000 milligrams daily.

"β-1,3/1,6-glucans and immunity: State of the art and future directions" by E. De Marco Castro et al., Molecular Nutrition & Food Research, 1/21

"Effects of beta-glucan on the immune system" by D. Akramiene et al., Medicina (Kaunas)

"Effect of pleural (β-glucan from Pleurotus ostreatus) supplementation on cellular immune response after intensive exercise in elite athletes" by M. Bobovčák et al., Applied Physiology, Nutrition, and Metabolism

Contributor

The Taste for Life Staff

The Taste for Life staff come from a wide variety of backgrounds and specialties. We believe learning is a life-long process, and love to share the knowledge we gain.

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Postbiotics

The next frontier in immune and gut health

By Nan Fornal

The microbiome has become one of the biggest wellness conversations of the decade—and researchers are increasingly focusing on one of its most intriguing compounds: postbiotics.

For years, probiotics (beneficial bacteria) and prebiotics (the fibers that feed them) dominated the gut health discussion. But scientists now believe many of the microbiome’s biggest benefits may actually come from the compounds healthy bacteria produce during fermentation. These compounds are called postbiotics. 

What Are Postbiotics?

Postbiotics are beneficial bioactive compounds created when healthy bacteria digest and ferment nutrients such as dietary fiber. Unlike probiotics, postbiotics are not living organisms. Instead, they are the beneficial byproducts and metabolites produced by microbes in the gut. 

Examples of postbiotics include:

  • Short-chain fatty acids (SCFAs) such as butyrate 
  • Peptides 
  • Amino acids 
  • Enzymes 
  • Microbial cell fragments 
  • Antimicrobial compounds 

Because they do not contain live organisms, postbiotics may offer advantages in stability and shelf life compared to traditional probiotics.

Exciting Research on Postbiotics

Emerging research suggests postbiotics may help support:

  • Immune function 
  • Gut barrier integrity 
  • Healthy inflammatory response 
  • Microbial balance 
  • Digestive wellness 

Researchers are particularly interested in the relationship between the gut microbiome and the immune system. In fact, much of the body’s immune activity is connected to the gut.

Studies suggest certain postbiotics may help modulate immune responses by supporting the intestinal barrier and interacting with immune cells and signaling pathways. 

One of the best-known postbiotics is butyrate, a short-chain fatty acid produced when beneficial bacteria ferment fiber. Butyrate helps nourish the cells lining the colon and supports the integrity of the gut barrier—an important component of immune health. 

Researchers are also studying postbiotics for their potential antimicrobial and anti-inflammatory properties, as well as their role in supporting immune resilience and healthy aging. 

Support Your Body’s Postbiotic Production

Healthy gut bacteria naturally produce postbiotics during fermentation. To support this process:

  • Eat a fiber-rich diet with fruits, vegetables, legumes, and whole grains 
  • Consider fermented foods and microbiome-supportive supplements 
  • Avoid unnecessary antibiotic use when appropriate 
  • Support overall lifestyle wellness, including stress management and sleep 

The Future of Microbiome Science

As microbiome research evolves, postbiotics are emerging as one of the most promising areas of gut and immune health research. While scientists are still learning exactly how these compounds work in the body, early findings suggest postbiotics may help explain why a healthy microbiome is so closely tied to overall wellness.

In other words: It’s not just about the bacteria themselves—it’s also about the beneficial compounds they produce.

 

“Butyrate in microbiome abates a host of ills, studies find,” University of Washington School of Medicine, 7/12/22

“Postbiotics: An alternative and innovative intervention for the therapy of inflammatory bowel disease” by H. Om et al., 2/24; “The potential of paraprobiotics and postbiotics to modulate the immune system: A review” by J.P. Mehta et al., 10/23, Microbiology Research

“Postbiotics and their health modulatory biomolecules” by E. Scott et al., Biomolecules, 11/4/22

“Postbiotics and their potential applications in early life nutrition and beyond” by C.A.M. Wegh et al., International Journal of Molecular Sciences

“What are postbiotics?” by T. Golen and H. Ricciotti, Harvard Medical School, www.Health.Harvard.edu, 11/1/21

“Why short chain fatty acids are important for a healthy gut” by M. Oliero, European Society of Neurogastroenterology and Motility, www.GutMicrobiotaForHealth.com, 4/26/23

 

Contributor

Nan Fornal

Nan Fornal has experience with fiction, nonfiction, and technical publications, working closely with book and magazine publishers from first edit to final proofing. She has worked with Exeter Press, Boston magazine, and self-publishers alike.

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